Research and Educational Activities of the BioNanofluidics and Microfluidics Laboratory

Welcome to BNML (Bioanalytical Microfluidics and Nanofluidics Laboratory)

Our lab is mainly interested in application of microfluidic and nanofluidic technologies to analyze important biomolecules such as proteins, peptide, RNA, and DNA. We are also exploring interesting physiochemical phenomena in microfluidic and nanofluidic systems that are not observable in conventional  macro-scale fluidic behaviors. Microfabrication technology, originally invented in the microelectronics industry, has been successfully employed to fabricate fluidic components such as channels, pumps, valves, mixer, and chamber in high precision and in a highly integrated fashion as can be seen below:

As a means of "plumbing", we are investigating effective methods of mobilizing biomolecules inside microfluidic device, such as electrophoresis, isotachophoresis , magnetophoresis, and dielectric phoresis. More complicated bioassay such as chromatin immunoprecipitation can be performed on chip by combining each mass transfer modality.  Prior to analysis of biomolecules , the molecules should be strongly immobilized  on microfluidic channel surfaces because the measurable signal is proportional to the amount immobilized (e.g., using electrostatic interaction in the following image). Our lab is also studying molecular interaction between biomolecules and solid substrate as a means of improving detection sensitivity.

Ultimately, we are pursuing microanalytical systems that can determine clinically and biologically important biomolecules accurately, rapidly, and reliably - so that they can replace bulky, expensive, material-consuming, but essential analytical instruments in research or clinical laboratory.


Graduate/Undergraduate Student Researcher Recruiting

BNML is currently seeking talented, active, and enthusiastic graduate/undergraduate students from all over the world. If interested in, please send me email with the heading "student researcher application", write why you are interested in my research group as well as how you can contribute to the group, and finally include your CV or resume.
현재 BNML에서 학부연구생/대학원생을 모집합니다. 특히 학부연구생은 기계공학실험 조교(미세유체실험) 업무를 수행해야 하므로 이 과목을 수강한 학생에 한하며, 사회진출장학금을 지급합니다. 관심있는 학생들은 이메일을 보내어 면담하시기 바랍니다.

Note: If you are from foreign institution (i.e., non-Korean), tuitions are all covered by Myongji University. We can discuss on stipend.

NEWS

5/30/2022
Jin Tae Kim (김진태), a 3rd-year undergraduate student, joined the BNML. Warm welcome to him.

4/19/2022
Jayoung Koo (구자영), a 1st year part-time graduate student, joined the BNML. Warm welcome to him.

4/4/2022
Bo Seok Heo (허보석), a 3rd year undergraduate student, joined the BNML. Warm welcome to him.

3/31/2022
The BNML receives a 3-year research grant from Samsung Science and Technology Foundation.

2/23/2022
The BNML receives a 5-year intermediate-level research grant from the National Research Foundation.

1/24/2022
Heeyeon Kim (김희연), a 4th year undergraduate student, joined the BNML Warm welcome to her.

1/23/2022
BNML publishes the paper "Quantitative Determination of 3D-printing and Surface-treatment Conditions for Directprinted Microfluidic Devices" to Biochip Journal (IF 3.494).

10/25/2021
BNML publishes the paper "Zinc-finger-protein-based Microfluidic Electrophoretic Mobility Reversal Assay for Quantitative Double-stranded DNA Analysis" to Biochip Journal (IF 3.494).

10/22/2021
BNML publishes the registered international patent PROTEIN MEMORY CELL AND PROTEIN MEMORY SYSTEM" (US 11,152,082).

7/27/2021
BNML publishes the paper "Cavitation-microstreaming-based Lysis and DNA Extraction using a Laser-machined Polycarbonate Microfluidic Chip " to Sensors and Actuators A: Chemical (IF 7.460).

6/16/2021
BNML presents two posters in the Biochip 2021 Spring Conference: "Cavitation-microstreaming-based Microfluidic Lysis and DNA-extraction Device" and "Quantitative Determination of 3D-printing and Surface-treatment Conditions for Direct-printed Microfluidic Devices."

5/31/2021
Haseul Lee (이하슬), a 3rd year undergraduate student, joined the BNML Warm welcome to her.

5/27/2021
The BNML receives a 1-year basic research fund from the National Research Foundation for the project titled "Acoustic microstreaming micromixer based on ultra-thin elastomeric membrane oscillator"

3/30/2021
The paper "­­Excitation-frequency determination based on electromechanical impedance spectroscopy for a Laser-microfabricated cavitation microstreaming micromixer" is just accepted to the journal Sensors and Actuators A: Physical (IF 2.904). The research was funded by Ministry of SMEs and Startups.

3/18/2021
An academiy-industry project based on our microfluidic technology is supported by the Mobile Division of Samsung Electronics.

3/3/2021
The paper "Inertial Microfluidics Enabling Clinical Research" is publihsed in the journal Micromachines (IF 2.523).This is an outcome of collaborated efforts with Hur Lab from Johns Hopkins University, USA.

2/6/2021
Jeonghwan Youn (윤전환), a 4th year undergraduate student, joined the BNML. Warm welcome to him.

1/10/2021
A master's student Hyunjin and an undergraduate student Hyeonkyu at the BNML finally graduated! Wish a great endeavor for them.